Free, open-source application for identification of cross-linked peptides from mass spectra.


  • Use virtually any stable cross-linker chemistry
  • Analyze isotopically labeled or non-labeled data
  • Supports open data formats (including mzXML and mzML)
  • Pre-compiled binaries get you started quickly

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Current Release

Version 1.5.5

Released on May 4 2017. Get your copy from our Downloads page.


We are open to collaborations on the analysis of protein structures using cross-linking technology. Interested parties should contact Dr. Michael Hoopmann.

15N analysis with version 1.6.0 alpha

June 9 2017

Thank you to everyone who said hello during ASMS. It was great to talk to so many users and get feedback. I appreciate all the ...